Update on the epidemiology of gastro oesophageal reflux disease a systematic review
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read more Subcription rates Select * The final prices may differ from the prices shown due to specifics of VAT rules. Article / Publication DetailsFirst-Page Preview Received: October 23, 2021 Number of Print Pages: 7 ISSN:
0257-2753 (Print) For additional information: https://www.karger.com/DDI AbstractBackground: The global pooled prevalence of gastroesophageal reflux disease (GORD) is approximately 14% and varies significantly according to the country. More population-based studies are needed in regions lacking epidemiological data on the prevalence of GORD, such as Eastern Europe, particularly Bulgaria. This current study aimed to evaluate the prevalence of GORD in Bulgaria and assess the risk factors associated with this disorder. Methods: An internet-based health survey was sent to Bulgarian adults. Individuals were invited to complete an online questionnaire on general and gastrointestinal health. The aim of the study was not explicitly stated. The survey collected data on sociodemographic and behavioral characteristics, validated questions to assess GORD, diagnostic questions based on Rome IV criteria to assess irritable bowel syndrome (IBS) and functional dyspepsia (FD), and questions about antisecretory drugs usage. Results: Data were collected from 1,896 individuals (mean age = 35.5 years, SD = 11.7, 73.1% females). The prevalence of GORD in the study population was 27.5%, while 57.29% of all GORD patients taking PPIs had PPI-refractory GORD. Age (p = 0.02), body mass index (BMI) (p < 0.001), marital status (p = 0.03), occupation (p < 0.001), sexual problems (p < 0.001), FD (p < 0.001), and IBS (p < 0.001) were significantly associated with GORD prevalence. Patients with FD (p < 0.001; OR 5.38), IBS (p = 0.03; OR 1.07), and with higher BMI (p < 0.001, OR 1.05) were at an increased risk of having GORD. Conclusions: The first data on GORD prevalence in the adult population in Bulgaria have been reported. Disorders of gut-brain interaction have a significant impact on the prevalence of GORD. © 2022 S. Karger AG, Basel References
Article / Publication DetailsFirst-Page Preview Received: October 23, 2021 Number of Print Pages: 7 ISSN: 0257-2753 (Print) For additional information: https://www.karger.com/DDI What is the epidemiology of GORD?GERD is one of the most common gastrointestinal disorders, with a prevalence of approximately 20% of adults in western culture. A systematic review by El-Serag et al. estimated the prevalence of GERD in the US between 18.1% to 27.8%.
How many people are affected by acid reflux in the world?GERD, Gastroesophageal reflux disease. The incidence of GERD is high in the general population, it is estimated to affect up to 20% of the population worldwide (12,13).
How many people in the UK have GERD?You're not alone: it's estimated that around 1% of the population – 500,000 people in the UK – have persistent reflux symptoms, despite taking the usual treatments, including high doses of medications.
What causes GERD scholarly articles?Epidemiology and Pathophysiology
Risk factors for GERD include older age, excessive body mass index (BMI), smoking, anxiety/depression, and less physical activity at work. Eating habits may also contribute to GERD, including the acidity of food, as well as size and timing of meals, particularly with respect to sleep.
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